Anti-Malaria should be given by weight, especially in children.
Chemoprophylaxis is not recommended in Pakistan.
While administering Chloroquine
P. vivax is fully susceptible to Chloroquine.
Intra-muscular or intravenous injections of Chloroquine should never be given. This
can cause sudden cardiac arrest.
While administering Sulfadoxine +pyremethamine (SP)
SP is not recommended for children under 2 months and during first trimester of pregnancy.
SP is not effective against Plasmodium vivax malaria.
SP is also not recommended in patients with known sensitivity to sulpha drugs.
While administering Primaquine
Primaquine should be given with Chloroquine only to microscopically confirmed vivax cases.
Primaquine should not be given to pregnant women and children under 4 years of age.
Primaquine should not be given to patients known to have Glucose-6-Phosphate Dehydrogenase
(G-6-P) deficiency.
Primaquine should not be given to patients who have received a complete dose of Artesunate + SP.
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